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Hands-On NGS Report Interpretation: Targeted and Comprehensive Genomic Profiling
Dr. Nguyen Duy Sinh delivers an interactive case-based session demonstrating how clinicians can confidently interpret complex NGS reports, resolve challenging genomic findings, and translate molecular results into clinically actionable treatment decisions.
Through a series of clinical scenarios, Dr. Nguyen Duy Sinh guides participants through practical interpretation of next-generation sequencing (NGS) reports across multiple cancer types. The session explores common challenges encountered in clinical practice, including EGFR and TP53 co-mutations, discordant MSI and mismatch repair results, HER2 amplification, RNA-based fusion detection, and interpretation of ctDNA-derived biomarkers.
The presentation emphasizes that genomic interpretation extends beyond identifying mutations. Participants learn how molecular context, biomarker interactions, and complementary testing modalities—including RNA sequencing and liquid biopsy—can substantially influence therapeutic decision-making. Special attention is given to emerging biomarkers such as tumor fraction, genome-wide ctDNA features, and RNA sequencing, illustrating how these technologies enhance diagnostic confidence and precision treatment selection.
This session equips clinicians with practical frameworks to interpret increasingly complex genomic reports and apply precision oncology principles in routine clinical practice.
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